Protein powders ranked by protein per calorie
Which protein powder has the most protein per calorie?
Of the 24 protein powders we compared, the most protein per calorie comes from 1UP Clear Protein Whey Isolate Lemon Italian Ice (20 g protein, 80 kcal), Isopure Zero Carb Whey Protein Isolate Unflavored (25 g protein, 100 kcal) and Dymatize ISO100 Whey Protein Isolate Gourmet Vanilla (25 g protein, 110 kcal). Every number is per scoop as labeled.
24 protein powders, each linked to its nutrition label · Updated
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1
1UP
Clear Protein Whey Isolate Lemon Italian Ice
1 scoop (27 g)
20 g protein
80 kcal · 0 g fiber · 0 g sugar · 125 mg sodium
25 g protein per 100 kcal
cdn.shopify.com · checked Sep 2026
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2
Isopure
Zero Carb Whey Protein Isolate Unflavored
29 g
25 g protein
100 kcal · 0 g fiber · 0 g sugar · 160 mg sodium
25 g protein per 100 kcal
theisopurecompany.com · checked Sep 2026
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3
Dymatize
ISO100 Whey Protein Isolate Gourmet Vanilla
1 scoop
25 g protein
110 kcal · 0 g fiber · 1 g sugar · 120 mg sodium
22.7 g protein per 100 kcal
dymatize.com · checked Sep 2026
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4
Isopure
Zero Carb Whey Protein Isolate Creamy Vanilla
1 scoop (31 g)
25 g protein
110 kcal · 0 g fiber · 0 g sugar · 190 mg sodium
22.7 g protein per 100 kcal
theisopurecompany.com · checked Sep 2026
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5
Bloom
Clear Protein Strawberry Watermelon
2 scoops (24.7 g)
20 g protein
90 kcal · 0 g fiber · 0 g sugar · 80 mg sodium
22.2 g protein per 100 kcal
bloomnu.com · checked Sep 2026
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6
Isopure
Infusions Clear Protein Tropical
1 scoop (25 g)
20 g protein
90 kcal · 0 g fiber · 1 g sugar · 15 mg sodium
22.2 g protein per 100 kcal
theisopurecompany.com · checked Sep 2026
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7
Clean Simple Eats
Protein Powder Simply Vanilla
1 scoop (25 g)
20 g protein
90 kcal · 0 g fiber · 0.5 g sugar · 65 mg sodium
22.2 g protein per 100 kcal
cleansimpleeats.com · checked Sep 2026
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8
Transparent Labs
Grass-Fed Whey Protein Isolate French Vanilla
1 Scoop (34.3g)
28 g protein
130 kcal · 0 g fiber · 1 g sugar · 180 mg sodium
21.5 g protein per 100 kcal
transparentlabs.com · checked Sep 2026
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9
Ascent
Native Fuel Whey Protein Vanilla Bean
1 scoop (31 g)
25 g protein
120 kcal · 0.5 g fiber · 1 g sugar · 60 mg sodium
20.8 g protein per 100 kcal
cdn.shopify.com · checked Sep 2026
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10
Premier Protein
100% Whey Protein Powder Chocolate Milkshake
2 scoops (41 g)
30 g protein
150 kcal · 1 g fiber · 1 g sugar · 170 mg sodium
20 g protein per 100 kcal
premierprotein.com · checked Sep 2026
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11
Premier Protein
100% Whey Protein Powder Vanilla Milkshake
2 Scoops (39 g)
30 g protein
150 kcal · 0 g fiber · 1 g sugar · 170 mg sodium
20 g protein per 100 kcal
premierprotein.com · checked Sep 2026
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12
Oath Nutrition
Clear Protein Icy Blue Razz
1 scoop (28 g)
20 g protein
100 kcal · 0 g fiber · 1 g sugar · 130 mg sodium
20 g protein per 100 kcal
cdn.shopify.com · checked Sep 2026
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13
Clean Simple Eats
Clear Protein Powder Pink Burst
1 scoop (28 g)
20 g protein
100 kcal · 0 g fiber · 0.5 g sugar · 30 mg sodium
20 g protein per 100 kcal
cleansimpleeats.com · checked Sep 2026
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14
Optimum Nutrition
Gold Standard 100% Whey Chocolate
1 scoop (31 g)
24 g protein
120 kcal · 0.5 g fiber · 1 g sugar · 130 mg sodium
20 g protein per 100 kcal
target.com · checked Sep 2026
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15
Optimum Nutrition
Gold Standard 100% Whey Vanilla Ice Cream
31g (About 1 Scoop)
24 g protein
120 kcal · 0 g fiber · 1 g sugar · 130 mg sodium
20 g protein per 100 kcal
target.com · checked Sep 2026
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16
Ryse
Loaded Protein Marshmallow
1 Scoop
25 g protein
130 kcal · 0.8 g fiber · 1 g sugar · 240 mg sodium
19.2 g protein per 100 kcal
rysesupps.com · checked Sep 2026
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17
Levels
Grass-Fed Whey Protein Vanilla Bean
1 scoop (32 g)
24 g protein
130 kcal · 0 g fiber · 2 g sugar · 125 mg sodium
18.5 g protein per 100 kcal
cdn.shopify.com · checked Sep 2026
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18
Oath Nutrition
Clear Protein Frosty Lemonade
1 scoop (30 g)
20 g protein
110 kcal · 0 g fiber · 1 g sugar · 150 mg sodium
18.2 g protein per 100 kcal
cdn.shopify.com · checked Sep 2026
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19
Owyn
Plant Protein Powder Chocolate
2 scoops (35.3g)
20 g protein
140 kcal · 2 g fiber · 4 g sugar · 300 mg sodium
14.3 g protein per 100 kcal
liveowyn.com · checked Sep 2026
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20
Owyn
Plant Protein Powder Vanilla
2 scoops (34g)
20 g protein
140 kcal · 0 g fiber · 4 g sugar · 240 mg sodium
14.3 g protein per 100 kcal
liveowyn.com · checked Sep 2026
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21
Orgain
Organic Protein Powder Chocolate
2 rounded scoops
21 g protein
150 kcal · 7 g fiber · 0.5 g sugar · 390 mg sodium
14 g protein per 100 kcal
orgain.com · checked Sep 2026
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22
Orgain
Organic Protein Powder Vanilla Bean
2 scoops
21 g protein
150 kcal · 4 g fiber · 0.5 g sugar · 390 mg sodium
14 g protein per 100 kcal
cdn.shopify.com · checked Sep 2026
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23
Orgain
Organic Protein + Superfoods Powder Chocolate
2 scoops
21 g protein
160 kcal · 9 g fiber · 1 g sugar · 390 mg sodium
13.1 g protein per 100 kcal
orgain.com · checked Sep 2026
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24
Orgain
Organic Protein + Superfoods Powder Vanilla
2 Scoops (51g)
21 g protein
160 kcal · 8 g fiber · 1 g sugar · 390 mg sodium
13.1 g protein per 100 kcal
cdn.shopify.com · checked Sep 2026
How this list works
- What made the list. At least 20 g of protein per scoop, from the packaged picks in Plenish's Explore tab.
- Per serving as labeled. One scoop, the way the brand's nutrition label lists it. Flavors and recipes change, so check the label before you buy.
- Checked against the label. Each item links to the brand's nutrition label, a retailer page that shows it, or USDA FoodData Central for whole foods. Numbers were checked in September 2026.
- Not a health score. This is a comparison of what's on the label, not diet or medical advice. Plenish isn't paid by any brand on this list.
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